Signal Transduction Reagents and Kits
Echelon Biosciences Research Labs Ins(1,3,4)P3 500 ug
Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,3,4-trisphosphate (Ins(1,3,4)P3) is an intermediate in the inositol phosphate pathway. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Ins(3,4,5,6)P4 in turn is responsible for inhibiting calcium-activated chloride channels. Ins(1,3,4)P3 is produced by dephosphorylation of Ins(1,3,4,5)P4 by a 5-phosphatase. Ins(1,3,4)P3 is a substrate for phosphatases yielding Ins(1,3)P2 and Ins(3,4)P2. This item is non returnable
Abcam Akt Kinase Activity Assay Kit
Akt Kinase Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Folic acid (10g). CAS: 59-30-3
Alternative name: Pteroylglutamic acid. Purity: ≥97% (HPLC). Solubility: Soluble in diluted acids or alkaline solutions; slightly soluble in water or methanol; almost insoluble in organic solvents. Long Term Storage: +4°C.
Apexbio Technology LLC Aurora Kinase Inhibitor III 879127-16-9 1mg
Aurora Kinase Inhibitor III (CAS 879127-16-9) is a selective small molecule inhibitor targeting Aurora A kinase It acts by binding to the ATP-binding site of Aurora A thereby suppressing its enzymatic activity with an IC50 of 42 nM The compound exhibits substantially lower inhibitory potency against epidermal growth factor receptor (EGFR) with an IC50 greater than 10 M Aurora Kinase Inhibitor III serves as a useful chemical probe for investigating Aurora A-mediated processes including mitotic regulation cell cycle progression and associated signaling pathways and supports studies exploring the role of Aurora A in oncogenesis
Selleck Chemical LLC Zolmitriptan 10mg 139264-17-8
Zolmitriptan is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Takara Bio Lenti-X GoStix Plus, 10 Minute quantitative lentiviral titer tests
Lenti-X GoStix Plus; Quantify lentivirus titer in 10 minutes; 50 Tests
Cell Biolabs Inc ViraDuctin™ Retrovirus Transduction Kit, 40 transductions
The rate at which retroviral vectors bind to and infect cells is mostly controlled by diffusion. During retrovirus infection, only a small fraction of the retroviral vectors can transduce target cells. Virion adsorption is the limiting step of this process. The use of polycations, such as Polybrene, is standard in many retroviral infection protocols owing to the observations of improved infection efficiency. Its mechanism of action is thought to involve neutralization of electrostatic repulsion between virion and cell membranes, enhancing attachment. ViraDuctin™ Retrovirus Transduction Kit is a proprietary formulation for the transduction of retrovirus. After forming a complex with retrovirus in culture medium, the ViraDuctin™ reagents typically provide higher transduction efficiency in many cell types compared to reagents such as Polybrene. It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 40 transductions.
Waters Corporation Upgrade Kit, Transducer BGM, for HPLC Systems
This upgrade kit is designed to update early 2545 Binary Gradient Modules in HPLC systems. It provides a newer style pressure transducer with a die-cast housing, along with tubing assemblies and an adapter, to replace older, round version transducers.
- Provides one pressure transducer and tubing assemblies.
- Updates early 2545 Binary Gradient Modules.
- Features a newer style transducer with a die-cast housing.
- Replaces older, round version transducers.
- Includes an adapter for installation to the pump head.
- Suitable for HPLC systems.
- Units per package: 1.
Creative Biomart Galsulfase, Human N-acetylgalactosamine 4-sulfatase
The product is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. The product is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular recognition. Post-translational modification of Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family.
Medchemexpress LLC Syk-IN-1 | 14911150-77-6 | 99.2% | 10 MG
Syk-IN-1 is a potent Syk inhibitor, with an IC50 of 35 nM. This compound is provided as a light yellow to yellow solid and is intended for research use only.
- Potent Syk inhibitor with an IC50 of 35 nM.
- Molecular weight: 366.42.
- Molecular formula: C18H22N8O.
- Appearance: solid.
- Color: light yellow to yellow.
- In vitro solubility: DMSO (100 mg/mL).
- For research use only.
Medchemexpress LLC UK122 TFA | 940290-58-4 | 99.85% | 405.33 | 100 MG
UK122 TFA is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. It exhibits minimal or no inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). This 4-oxazolidinone analogue acts as an anticancer agent that hinders cancer cell migration and invasion. This product is intended for research use only.
- Potent and selective uPA inhibitor
- Inhibits cancer cell migration and invasion
- Minimal inhibition of tPA, plasmin, thrombin, and trypsin
- Suitable for in vitro studies
Takara Bio RetroNectin GMP grade, 2.5 mL
Enhanced gene transfer efficiency for retroviral or lentiviral transduction of suspension cells, hematopoietic stem cells, and other hard-to-infect cell types.
Medchemexpress LLC Malic enzyme inhibitor ME1 | 522649-59-8 | 99.7% | 351.40 g·mol⁻¹ | C20H21N3O3 | 50MG
Malic enzyme inhibitor ME1 is a small-molecule, selective inhibitor of cytosolic malic enzyme (ME1) used for biochemical and cellular research. It exhibits potent inhibition of ME1 (IC50 = 0.15 μM) and is supplied as a white to off-white solid with high purity and defined storage recommendations.
- Potent ME1 inhibition (IC50 = 0.15 μM).
- High purity suitable for biochemical assays (99.7%).
- Supplied as a solid, white to off-white.
- Highly soluble in DMSO; may require sonication and warming.
- Stable when stored under recommended conditions in powder or solution.
Sigma Aldrich Fine Chemicals Biosciences Zolmitriptan Related Compound H United States Pharmacopeia (USP) Reference Standard | 1116-77-4 | MFCD00671479 | 50MG
Zolmitriptan Related Compound H United States Pharmacopeia (USP) Reference Standard | Mol Wt: 189.3 | 1116-77-4 | MFCD00671479 | 50MG
Enzo Life Sciences 8-Bromo-cGMP (50mg). CAS: 51116-01-9
A cell-permeable cGMP analog which is more resistant to phosphodiesterases than cGMP and which preferentially activates cGMP-dependent protein kinase. It inhibits thrombin stimulated arachidonic acid release in human platelets. Purity: ≥96% (HPLC). Solubility: Soluble in water (25mg/ml) or aqueous buffers. Sparingly soluble in methanol (4mM). Insoluble in DMSO, dimethyl formamide and 96% ethanol. Long Term Storage: -20°C.